SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6a001048c71a93dd0a3e6c94258b51d69f17c2cb1e49de24083454442115ac' 
  AND token = '9xyrmApIpnH0rlnyhYWHgl4dNq4VACFosf0OOTMaP5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}