SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37001f3f779e146b81107539b4e86aec75ba2810a074d39df7224365e7bfb695' 
  AND token = 'sEqG3dNTW3bkQhO7EF1OxRVVoZTIhAVyt7NY250jzPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}