SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eac58c7de72216f377b2896450a268f148c0fa76d91f8b70785a46828db2fc5' 
  AND token = 'QeD/scEUBs9zCq9+Jz6E+FNWqWd7QWhrq18UntUt/Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}