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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '613ee5c527c5d5d9a41d53d893b0035d8c8d973054c03600a36335a250774219' 
  AND token = 'C1TXHlNNDoGBaLF+f4lv1BSOi3Nv33y62EpJ6nxGAiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}