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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885f3a843be0d6037186e8b6e27d0d2baa421321538544aee3496332eb780c9a' 
  AND token = 'TB+BfX3HK33sogrj59npZRQQYgxWaoKRb/OeITFq5co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}