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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef2d4acf703b694f3aaaeed89d7dd790ab2f1d198d59ebb5d6a5e2c2329c7a8' 
  AND token = 'lZH6goGRcljtB/kb3FFvD9PP4fMCv+aSa9sG6t5PMgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}