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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a75466259c4a545ef13526791177184b44df4a95c2fc7891f14854eab24cf8' 
  AND token = 'WH7UzZsos9f+LTaDrrqB4AYjsQeq2t2hfGFIIGHFbPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}