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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fcb9226bf3cb0e58535a7fe6eeded2cc9b0ca02f2bc98976ea79dd13a9d2448' 
  AND token = 'JolXRjQ8zlPlL2B32u7Dz+LmtsnWL56x0UtSOmFxSHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}