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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cd9cf28e67a55c1faf6ed5b6c3a589b315291557417fa38172d0216f8eab53' 
  AND token = 'VkTIM3LdQToDCvIB/mtviM/wmjCvhIzbo5xtW1EyR98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}