SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f37b1fd81d80d97832f2be17a4d85ad04b695b3c052bee143accf8bd905c0ee' 
  AND token = 'llRTRJlGDKn8qrFNB1t163FIR8XTwsaW1+XpU3e/qyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}