SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db9ce9b553ed42a5de5809d2c35b920f75c69059604f5d54f911b30e21a1e59c' 
  AND token = 'zua/KLBVCLF5mnKkvXjykxdGHyQSMQQUsymqq/jAjoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}