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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec6e15b17de727540ff3939b52b216bee357da41c826b61a5d669592028de59' 
  AND token = 'Vdkyb/TVjDanLZ5tmD9X3uzQfa3a1dFJ6AwPnlwbTGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}