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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c1346a781100730c6d8febcd62ef7e9a7fa5cae6a1519f432be24e9a3146d5' 
  AND token = 'VkuZ0HH3PNQG9bPUF12Qg17/Y/tAoTc4T8WlqHzF9vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}