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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca27c1ebdade1c0eac74e997c9b8a0d392fe55129025e71170c95f2b43f4c69' 
  AND token = 'cgz2b88lQaBPUTWTxeoT+niLX5cdbTsYEuRBU4aZeN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}