SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b43b1ba1db35d4a7e43fcd30e65400d740df95b6ea9d41e43e517873155e02f' 
  AND token = '6gqU7r4jFsxfnYgCX/QCrq817LtTn8sXs2qh0Fqp0Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}