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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9684aa43b390202002b77c795a0d4cdf7850c39c7f78f80faf1305eb98edf276' 
  AND token = 'cr+hsvIC1d4QQcY9VRXEHE3oRgZhhD3L/XjHH0yEq4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}