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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59908185e46921600a5c2a4e0a68cdd52ff6d3083c47fdb8df6921f33b6d0e1' 
  AND token = 'qyjtOxcEjOz6Fl8jLjCP9MnedhJ9ScZAhMv0LwpR878=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}