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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4335c31d59dedac0e57d340ab69cacc437088caf47d84982a0ef320d52bbfd15' 
  AND token = 'VEIO8Zyrobe4/P+cabEHpGNE31qlRzBt8uqo9dkAZ+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}