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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f2189f20a9c7bd66be442fcf8261e7ad2081ad255f051a11cb895197ea9258' 
  AND token = '3v+x+lIIeQM+TLy9IyVuRvFlmkKT14lSRz02EDpHwRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}