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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a296fddcaeb79bbcf16351a60fee5c2cb099697e0a9a56534e8befc3639c1be0' 
  AND token = 'mxUrsUYu3VtSQifUTzZ92Y55ORUJCKJAEV73aTJwvY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}