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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729ce9a224484368191b9164d27fb5c2cb1f769ef0c1e97e83ca3cd02ae911bd' 
  AND token = 'XcBQ6FmFwefWvBchvCGHhGdPc9guPYAtpxhHFOkM5Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}