SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18040d253c530bde667766b8463cf59be8d1207b28b2ad5359fe53c60c45e091' 
  AND token = '/55BJGEC0fHvCQWMYQRtyo4HCng1JZikW1jq9Eri7V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}