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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee36ce7f16b8f4ce09fd317e3682d12b4048f9313be2c91f768c60da0cb2f36f' 
  AND token = 'Imr2H4pfo2T5t6vlZldLgZDLADKmHNP5RDDm+dAbuAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}