SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '476499cd9199663762e48bbd0a37f918a3e36c842e50928878898ecd8bb2c667' 
  AND token = '/RJYHk1DTf2QxC4Ui+BmmA5f23ZyktI5+FaJHO7EZbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}