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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80d218bc627035c0189edd9bea87ebee8d0a9cdc272668230f9eb19104f495e' 
  AND token = 'bAA+CFQnOlR/9/OoaYsQgXiAI+DBRpVx2UU6MPpfJRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}