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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99afb5ab11ffda0a4521e2a2a98df15e1059186d6dcbbbf5a25d9deb6c181f43' 
  AND token = 'RHGEDBFLpLnAPbGItcbWimb/+d/ohQ4ZnfbV3Z/Z++M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}