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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8509dd7c3a325a5b35714a8882afe487264a7a5f9a5f047eed24dd328ae8b377' 
  AND token = 'bpeKNcBjXgCzeyw4BPTu1Z2+hTrEyRLCclpXmRqiBfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}