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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1790b1529b4dcb4c56fdc0d9c158624efbcddecd420c6f6c8406bfe63dce7bb3' 
  AND token = 'xtdgFLDFKxUo0viROVuOq1YmQN+47pKTBt0lp/HPTsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}