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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee4879fddfc235980e269457dd7475a3ef5827aef7a4ff5c4d944e06f90e20f4' 
  AND token = 'MSPO9wz5eaiwaDq+lmZ4mBvhMofBhfMe5OPxudu8CyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}