SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c915ec2501d59d7b6ab64a311c0ffa9f8de98fc0c001f31189c3464ffac748' 
  AND token = 'ZD1ZGV99EykBNOVq5TV57x/hTX571/LMl5Tm7kTZg0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}