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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484f602ba1e587804e2faa47e314b36049ff03113d4e9e18ac9835728b3134d4' 
  AND token = 'Q4mSwPqWDZ4cE2lVTz/G+thoJLt6P9MaAHXiZxQo/I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}