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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5e421f52d62208025500dd2f25d46eef31f8120ade1d8d7d8b7c4972dd3db7' 
  AND token = 'lRTb6uDSww9Y524X30E4IV0sTp7LdVDjex20Z+uxC7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}