SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fdb5bee5fdfea069ad36d204719e2d624ae5c8f19c9cfd69aa05f3c383cedd5' 
  AND token = 'p6q0BmE63S5Ll+I/l1B6p59Ih5unFD5a6XUeMdQVL8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}