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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed53c705b23273077d33dd59dd6c1d789acd7b469774d71fe6a4315d1e1aff5' 
  AND token = '2JPgv/sWHLIvzd3jrwJ01aPyAps/+6PI8zQI/uyP0nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}