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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14de625addd24f2c73280ca91110ce4b5a8ce758f341cc04cd3cca42db9cf65' 
  AND token = 'eGnGN2tvSMOX3fKh1FHhtxF827Yh386/tCxKD9WZpXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}