SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3665c3d72904ba24825a6f0f2a481c7b3ffa5212bed83a259ddca55fc2565a33' 
  AND token = 'PboesSWLsQBkvYH1sCeuxbV9vKtI5IIOyca47+jbtow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}