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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a221a0030b940c9f00b6ac17201d98de6baee2780faaf141688ca1a62f2b6e04' 
  AND token = 'QBDpIOcWBqPBglyAbqcURLVxRrWSBiLq7VplXL9uE64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}