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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e4244419ad7f5e24378f47683fbe3414c620eeaab533602284a50107c293b4' 
  AND token = 'j2edpQL0U5eDdiSV7Ol0pfpLq2IH9fthfEAoBLrz+9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}