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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '199a429faf5b1081641ce82cf865d4ae1e34214c4fdfa37f44ea7a25a4b1d666' 
  AND token = 'f3jo0WbO57Keudo5gWHCplXeTT0oBIy1UpdJZ04K3Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}