SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85b66d210446dde83fbacf2df40613023dd8d28ada1917d8b2faa39851be148a' 
  AND token = 'DbFSHO3fqpD+ukS+Pn6TAPUwIUNuYta4sDGc0uHlbFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}