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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b0167bbfd718d0a6f5421512947aca69d792fc536c05a6f4f469a02dd2efe1' 
  AND token = 'OXI5HNFN4mPqGTSz3j5LQ/mpcZw5Vi+pkL6faSxG2eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}