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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f00b162f924bf7ad006054f807c70610382022fe9ab33fe0faf3fbd4a8183a6' 
  AND token = 'bpAoCtELatXGv6fjK2DSPKWc++mGKAGpc0KdhLtecUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}