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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e80d45d0c039f384fc51217cd0b04ab2bc0b6d8b7e6ceb94502d27685943fde' 
  AND token = 'tJ3yua5YZepxk/ajyq2b1oIRQ4mnKRYefakuCqGv+4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}