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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2441e40343f6debee1bcbd90bb525c79ebe374e4f01e3d5487d6c5afe409b917' 
  AND token = 'LrgmXYe64rRS1vo6Uj+K2GGrRH66ZRPhcoZ1KIIDbwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}