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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f10eed1b505100286abd022ec6f5b133dfc79aefc72e23069bd59c020ef786c' 
  AND token = '2XcWnGA6sEjYNyddEJYr+CqsVk/YBycEwtV5Ray8Mb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}