SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d75ac76276cb90ebde9715e664526aec36fe215a20dc23b6fc5591287e971e' 
  AND token = 'rOVUz7YQ2Ih/RqLbmtyJB2d82vUgxaLlBl7Ncc8d4zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}