SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c78ee5ae00155393b796d87a0eaf974fc7bfaf0aa40b30dc41eeae36fc3800' 
  AND token = 'GPallJl/COz2LfZW0koLq/VbehcKR7vymPw/0t6Rv2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}