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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a5803e6aa633cee6e55d866a1cf6085029c7bd4cdf7d8cf4e76826bbd27fc8' 
  AND token = 'OrWCXVuPIy1MzF14E2WG6/ZfabCf0fu6YHeh4ytRjeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}