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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289476a450ca8d8e8703763fb585e153153ce4cb98079c42082b811471396df9' 
  AND token = 'PCByUMj5oKitQetuj11QHjon4P0FH2zWjg2mtdM5CQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}