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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e2f94f568f3f6809025e70d6e1c9ab493eb3aa0dc73def7124ffd1b455c21c' 
  AND token = 'StWs59TEK+vuPGaFBUG+Sh2+s6+saiFGvQuuj6S1sJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}